Uh-Oh - looks like MJ's doctor did administer deadly drug!

[steveo777]

LOS ANGELES — Michael Jackson's personal doctor administered a powerful anesthetic to help him sleep, and authorities believe the drug is what killed the pop singer, a law enforcement official told The Associated Press on Monday.

http://www.foxnews.com/story/0,2933,534991,00.html

This is fucked up beyond words, if this is really what happened. Without this Doc's handy work, MJ would still be alive. So is this criminal or civil malpractice?

[portland]

LOS ANGELES — Michael Jackson's personal doctor administered a powerful anesthetic to help him sleep, and authorities believe the drug is what killed the pop singer, a law enforcement official told The Associated Press on Monday.

http://www.foxnews.com/story/0,2933,534991,00.html

This is fucked up beyond words, if this is really what happened. Without this Doc's handy work, MJ would still be alive. So is this criminal or civil malpractice?

It's just plain fucked up!

[RaisedOnRadio92]

Because of who Michael Jackson was, he'll be charged with murder. If it was a regular human being, it would be an accident.

[portland]

Yeah well in the hospital I work in you just don't bring that drug home with ya.....if you know what I mean. Never should have happened and somone needs to make sure it does not happen again.

[steveo777]

I edited the thread title, as I felt it better that people know what the thread is about.

[RaisedOnRadio92]

Yeah well in the hospital I work in you just don't bring that drug home with ya.....if you know what I mean. Never should have happened and somone needs to make sure it does not happen again.

Knowing Michael, he probably paid a million bucks to the hospital to let him take it home.

[Babyblue]

You are so right.The Dr ass is going to burn big time.

[steveo777]

Yeah well in the hospital I work in you just don't bring that drug home with ya.....if you know what I mean. Never should have happened and somone needs to make sure it does not happen again.

Knowing Michael, he probably paid a million bucks to the hospital to let him take it home.

Exactly! People can get anything they want with the right kind of money.

[T-Bone]

A "Stroke Of The Pen" can change any law out there. I'm sure MJ stroked pens as well and had his very own uber-stash of this shit

[Babyblue]

He should not have left him at anytime.You should have stayed there to make sure he was breathing.He had drugs everywhere from what i understand.

[steveo777]

A "Stroke Of The Pen" can change any law out there. I'm sure MJ stroked pens as well and had his very own uber-stash of this shit

Still, however this stuff is used to put people down for surgery and they also need to be brought back up. So, even if he had the drug, he would know that if he took it by himself he would not come to by himself. Knowing that, the doctor had to give it to him and that is where the culpability lies.

[RaisedOnRadio92]

"... He would decide what time he wanted to awaken and at the appointed hour a doctor would stop the intravenous drip that delivered the drug, the official said."

Wow.....that's unbelievable. Ya know, I haven't heard this theory, but he probably had been having minor surgeries in his own home with his private physicians.

[Chubby321]

This doctor will the most hated doctor in the world right now.

[steveo777]

This doctor will the most hated doctor in the world right now.

While he may never practice medicine again he may be assured of meeting many self professed proctologists in prison.

[Jana]

He was going to die of a drug overdose or drug-connected deathy anyway. it was just a matter of time with the addictions he had. What is so strange to me is the way these doctors who make good money can be swayed by attachment to a celebrity and the money to put their career and freedom on the line. And what boggles the mind more is they have seen the problems with Anna Nicole's death and others and the investigation into the doctors. Wouldn't that make them more cautious? Guess not.

[mikemarrs]

sounds like elvis presley and his situation with dr. nichopoulous.very similar in many ways.

[slucero]

it was a little known drug called... "dirtnapiville"

[RaisedOnRadio92]

This doctor will the most hated doctor in the world right now.

While he may never practice medicine again he may be assured of meeting many self professed proctologists in prison.

LMAO!

[strangegrey]

This is fucked up beyond words, if this is really what happened. Without this Doc's handy work, MJ would still be alive. So is this criminal or civil malpractice?

hNot to bring such an obvious 'up' side to such a down side, but He probably saved countless children from the lasting and painful effects of sexual abuse....

[Rhiannon]

And no one is questioning the veracity of these reports here either, I see?

-----

LAS VEGAS, Nevada (CNN) – Investigators carrying search warrants arrived at the Las Vegas home of Michael Jackson's personal physician, Dr. Conrad Murray, on Tuesday morning, according to a source close to the investigation.

Dr. Conrad Murray was with Michael Jackson on the day that he died.

The investigators, including Los Angeles police and Drug Enforcement Administration agents, entered the home at 9:15 a.m., the source said.
The search comes a day after a source with knowledge of the investigation confirmed to CNN that Murray administered a powerful drug that authorities believe killed the singer.
The Texas-based cardiologist allegedly gave Jackson the anesthetic propofol — commonly known by the brand name Diprivan — in the 24 hours before he died, the source said.

-----

By the way, on CNN last night the reporter cited RadarOnline.com as his fucking source. A gossip site. As a source for CNN? I think I'll do the educated thing and wait on official releases from the LAPD (who still officially contend that Murray is no suspect nor is there a manslaughter investigation).

Notwithstanding we're over a MONTH out from the death. And remember, there has been no release of coroner/autopsy/toxicology findings yet. Which the last official statement regarding that was a month ago from Ed Winters, "We expect the results back in 3-4 weeks. There is nothing to suggest evidence of foul play."

Murray was also "allegedy" not home during this "alleged" raid on his home. So where is he? And why aren't there any paparazzo shots of him after 5 weeks?

I call bullshit to everything the "media" "reports" until it is verified and cited, and not just speculative trash.

Screw ABCNNBCBS.

[Rhiannon]

PS... Diprivan is not an addictive drug. And no REM sleep occurs during its use. Jackson would have been dead LONG before now if this "he used it regularly" shit were true.

[bluejeangirl76]

and p.p.s. - um.... where's the BODY?

[Rhiannon]

This is fucked up beyond words, if this is really what happened. Without this Doc's handy work, MJ would still be alive. So is this criminal or civil malpractice?

hNot to bring such an obvious 'up' side to such a down side, but He probably saved countless children from the lasting and painful effects of sexual abuse....

More speculative trash.

[Lora]

By the way, on CNN last night the reporter cited RadarOnline.com as his fucking source. A gossip site. As a source for CNN? I think I'll do the educated thing and wait on official releases from the LAPD (who still officially contend that Murray is no suspect nor is there a manslaughter investigation).

Notwithstanding we're over a MONTH out from the death. And remember, there has been no release of coroner/autopsy/toxicology findings yet. Which the last official statement regarding that was a month ago from Ed Winters, "We expect the results back in 3-4 weeks. There is nothing to suggest evidence of foul play."

Murray was also "allegedly" not home during this "alleged" raid on his home. So where is he? And why aren't there any paparazzo shots of him after 5 weeks?

I call bullshit to everything the "media" "reports" until it is verified and cited, and not just speculative trash.

Screw ABCNNBCBS.

The masses feed on this garbage so that is why the news stations keep throwing the trash out there.

[kathyhelms]

Propofol (2,6-diisopropylphenol) is an intravenous, nonbarbiturate anesthetic that is chemically unrelated to other intravenous anesthetics. Propofol is used to induce anesthesia that can be maintained by continuous infusion or with inhalation anesthetics. Propofol induces anesthesia as quickly as thiopental, but emergence from anesthesia is 10-times more rapid than with thiopental and is associated with minimal postoperative confusion. Only desflurane has a more rapid recovery time than propofol, but desflurane is associated with nausea/vomiting.[23940] Propofol has no analgesic activity and causes sedation at a lower dosage than that needed for anesthesia. Unlike many other general anesthetics, propofol possesses antiemetic activity. Propofol (Diprivan®) received FDA approval in October 1989. In March 1997, the FDA granted exclusivity until 2015 to Zeneca for a modified formulation that contains disodium edetate (EDTA) to retard microorganism growth. A generic formulation of propofol is available, but it contains sodium metabisulfite and not EDTA as the perservative.
IntravenousAdministration
•Only administer by intravenous (IV) administration by individuals trained in the administration of general anesthetics when used for general anesthesia or monitored anesthesia care sedation.
•Although not a controlled substance, propofol has been abused. Access restriction and accounting procedures are recommended.
•Strict aseptic technique must be followed during handling as the lipid-based vehicle is capable of supporting rapid growth of microorganisms. Disinfect the rubber stopper of the vial or prefilled syringe with 70% isopropyl alcohol.
Administration for ICU sedation directly from the vial must be completed within 12 hours of spiking the vial; discard tubing and any unused portion after 12 hours. If transferred to a syringe or other container before administration for ICU sedation, discard unused portions and IV lines at the end of the procedure or within 6 hours of opening the generic propofol vial or within 12 hours of opening the Diprivan® vial, whichever is sooner. For general anesthesia or procedural sedation, draw into sterile syringes immediately after opening the vials. After vial is spiked, complete administration within 6 hours for generic propofol and within 12 hours for Diprivan®. Discard unused portions, reservoir, dedicated administration tubing, and solutions containing propofol at the end of the procedure or within 6 hours of opening the generic propofol vial or within 12 hours of opening the Diprivan® vial, whichever is sooner. Flush the IV line every 6 hours for generic propofol and every 12 hours for Diprivan® and at the end of the anesthesia procedure.
•Possible cardiopulmonary adverse effects of propofol include respiratory depression, apnea, hypotension, and sinus bradycardia. Apnea is most common during anesthesia induction. Of 1573 adult patients that received induction with 2—2.5 mg/kg, 43% had apnea whereas 27% of 218 children had apnea after receipt of 1—3.6 mg/kg. The duration of apnea is usually between 30 and 60 seconds, although it was longer than 60 seconds in 12% of adult and 6% of pediatric patients. Hypotension is the most frequently occurring cardiopulmonary effect, reported in 3—10% of adult patients and in 17% of pediatric patients. The drop in arterial blood pressure can be more than 30% and is due to reduced preload and afterload. Patients may experience dizziness, although < 1% of patients reported this event during clinical trials. Administration of intravenous fluids or pressors and extremity elevation may be needed. There is usually little to no change in heart rate or cardiac output with the drop in blood pressure for patients that are breathing on their own. In contrast, a reduction in cardiac output and a greater extent of cardiac output depression are more likely for patients with assisted or controlled ventilation. Sinus bradycardia that occurs during a maintenance infusion may be due to a reduction in sympathetic activity or a resetting of the baroreceptor reflex. Propofol has no vagolytic activity. If the inhibitory effect on the heart is detrimental, administration of an anticholinergic drug to modify the increased vagal tone should be considered. Hypertension, sinus tachycardia, premature ventricular contractions (PVCs), premature atrial contractions (PACs), abnormal ECG, QT prolongation, ST-T wave changes, asystole, and cardiac arrest have occurred rarely (< 1% of patients). Fatal cardiac arrhythmias have been seen within 40—60 hours of therapy with propofol > 5 mg/kg/hour in patients with head trauma. Supraventricular tachycardia (SVT) with initially widening QRS seems to be a warning sign of these fatal arrhythmias. Cardiopulmonary adverse effects are largely dependent on the extent of premedication, propofol dosage and rate of administration, and underlying medical conditions. Cardiorespiratory depression is more likely with higher blood concentrations of propofol, which can result from the use of bolus doses or rapid increases in the infusion rate. Debilitated or elderly patients, and those with severe cardiac disease appear to experience more exaggerated responses. Patients with preexisting cardiac conduction abnormalities may have an arrhythmia exacerbation. The cardiovascular depressive effects have been attributed to direct vasodilation and negative inotropy. The respiratory depression may be due to direct suppression of the central inspiratory drive. If hypotension and respiratory depression are profound and refractory, overdose should be suspected.

To date, there has been no association of malignant hyperthermia with propofol. However, neuroexcitatory symptoms have been associated with propofol during and after drug administration. Neuroexcitatory symptoms may be a result of an imbalance between cortical and subcortical structures and decreased inhibitory output from the formatio reticularis. Perioperative myoclonia, rarely including seizures and a dystonic reaction known as opisthotonus has occurred with a temporal relationship to propofol administration. In clinical trials, hypertonia/dystonia occurred in < 1% of patients. Very rarely the use of propofol may be associated with the development of a period of postoperative unconsciousness that may be accompanied by an increase in muscle tone. A period of brief wakefulness may precede the event and recovery is spontaneous. There have been several cases reported in the literature. One patient became unresponsive and developed massaeter spasm 2 hours after propofol cessation. She awoke after 6 hours and reported being awake during the event. Symptoms occurred in most patients after regaining consciousness, within 7 hours of propofol cessation, and persisted for less than 24 hours, although symptom duration was longer in about a third of patients.[27362]

Propofol is isotonic and has a pH between 7.2 and 8.5. An injection site reaction, characterized by burning, stinging, and pain, has been reported in 17.6% of patients enrolled in clinical trials. However, immediate or delayed discomfort may occur in as many as 90% of adults and 85% of children. Phlebitis or thrombosis occurred in < 1% of patients in clinical trials. If extravasation occurs, local pain, swelling, blisters, and tissue necrosis may occur. Propofol is directly irritating to the venous intima. Propofol also activates the kallikrein-kinin system, which results in bradykinin production. Bradykinin dilates and increases the permeability of the vein. As a result, the aqueous-phase propofol irritates more free nerve endings outside the endothelial layer of the vessel. Less frequent reactions include tingling, numbness, and coldness. Options to decrease discomfort include use of the larger forearm veins, such as those of the antecubital fossa or the use of lidocaine 40 mg or granisetron 2 mg both in normal saline retained in a tourniquet-occluded vein for 2 minutes. The drugs similarly reduced the severity and incidence of pain associated with propofol injection. Lidocaine 1 ml of a 1% solution is commonly used. Other options that have been shown to reduce pain on injection are tramadol 50 mg and ondansetron 4 mg injected into a vein on the dorsum of the hand after a tourniquet has been applied to the forearm. The tourniquet is released after 20 seconds and propofol administered.

Anaphylactoid reactions that may include bronchospasm, erythema, hypotension, wheezing, laryngospasm, and angioedema have occurred shortly after administration of propofol. Anaphylactic shock is also possible. Because of concomitant use of other agents, a causal relationship has not been established. Likewise, pulmonary edema has been reported rarely with propofol, but a causal relationship is unknown, although a temporal relationship has been shown.

The FDA has received reports of several clusters of patients who have developed fever, chills, and body aches that began 6—18 hours after propofol receipt and persisted for up to three days. As of June 2007, all affected patients received propofol for sedation in gastrointestinal suites; in some cases, a vial was inappropriately used for more than one patient. No evidence of contaminated propofol vials and prefilled syringes exists, as determined by bacterial contamination testing of multiple units of propofol vials and lots that have been associated with the adverse events experienced by patients. Testing of other potential sources has also not identified any potentially causative agents. All patients recovered without apparent sequelae, but several patients have been hospitalized and one patient had seizures; no evidence of bacterial sepsis was noted. Sepsis should be considered in patients who develop hypotension, chills, fever, body aches, or other symptoms of an acute febrile reaction shortly after receiving propofol for sedation or general anesthesia; blood culture attainment and antimicrobial institution may be appropriate. Most studies with propofol have not examined infectious complications (other than contamination) as an outcome.[26919] Failure to use aseptic technique when handling propofol has been associated with microbial contamination of the product with fever, infection, other life-threatening illness, and/or death. Microbial contamination of propofol may occur even with use of aseptic technique. Propofol is not a microbially preserved product according to USP standards and thus, can support rapid growth of microbial organisms. Propofol is a single-use parenteral product; discard any unused portion within the specified time period (see Administration). Use of strict aseptic technique, adherence to the single-use requirement, and discarding of unused product within the specified time limits are paramount for safe use of propofol. Do not use if contamination is suspected. As determined from in vitro data, propofol may interfere with lymphocyte function, neutrophil function, and cytokine release. The clinical significance of these effects is unknown but may be greater when propofol is used for extended periods of time. Also, data have suggested that intravenous lipids (including propofol formulations) may alter the immune response to infection (e.g., interference with leukocyte migration and interleukin-2 dependent lymphocyte response). Healthcare providers are encouraged to report adverse events to the FDA's MedWatch Adverse Event Reporting program by calling 800—332—1088.

Propofol withdrawal syndrome has been described in a burn patient with concomitant bipolar disease receiving continuous IV infusions of propofol for 95 days to control extreme agitation and assist in ventilation. With each attempt to discontinue propofol, the patient required a restart of the propofol infusion to control abrupt agitation, tremors, tachycardia, tachypnea, and hyperpyrexia.[27575] Long-term infusions of propofol are controversial and no longer supported by the manufacturer, although long-term infusions have been administered without evidence of withdrawal. Although additional case reports of propofol withdrawal syndrome exist, the data are variable and inconclusive as to predict the risk factors for withdrawal. Withdrawal symptoms have been reported in patients with a duration of propofol infusion from days to several months.[27576] A propofol weaning protocol has been suggested (see Contraindications).

[Shadowsong]

Yikes, doesn't sound like a drug for anyone to play with at home!

[squirt1]

Yes, there are some doctors that will so anything for $100.000.00 per month. They rationalize their risk of criminal & civil stupidity just like many in society. Only the toxicolgy report will tell if he got drugs that this doctor did not supply from another source. A shame he was in so much mental pain.

[JasonD]

Can we hook MJ's doctor up with that lady in T-Bone's thread who decapitated her baby?

I'm just saying........................

[JeremyP]

hNot to bring such an obvious 'up' side to such a down side, but He probably saved countless children from the lasting and painful effects of sexual abuse....

Why do you do this, man? Does it help you sleep better?

[Vladan]

Yeah, blame the doctor? why not, they have to blame somebody for MJ's death. The nerve of these idiots... it's not the doctors fault, they are so dumb beyond words... let him rest in piece, makes me sick reading all these articles, just cashing in on the man's death some more.

Just wait till people start coming out of the blue with false sexual abuse stories... it won't be long now.